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Bartolomeo Gosio : ウィキペディア英語版 | Bartolomeo Gosio
Bartolomeo Gosio (17 March 1863 - 13 April 1944) was an Italian medical scientist. He was the discover of a toxic fume, eponymously named "Gosio gas", which is produced by microorganisms, that killed many people. He identified the chemical nature of the gas as an arsenic compound (arsine), but incorrectly named it as diethylarsine. He also discovered an antibacterial compound called mycophenolic acid from the mould ''Penicillium brevicompactum''. He demonstrated that the novel compound was effective against the deadly anthrax bacterium, ''Bacillus anthracis''. This was the first antibiotic compound isolated in pure and crystallised form. Though the original compound was abandoned in clinical practice due to its adverse effects, its chemical derivative mycophenolate mofetil became the drug of choice as an immunosuppressant in kidney, heart, and liver transplantations. ==Biography==
Gosio was born in Magliano Alfieri, Piedmont, Italy. His father Giacomo Gosio died just when he completed his elementary education, and was brought up by his mother Antonietta Troya. He studied medicine at the University of Turin and continued at the Royal University (Sapienza University of Rome). He received his medical degree in 1888. He was appointed at the Laboratory of Bacteriology and Chemistry of the National Hygiene Institute (''Istituto Superiore di Sanità'') in Rome. Then he went for further training to Max Rubner in Berlin. In 1899 he became director of the Scientific Laboratory of the Public Health Service (''Laboratori Scientifici della Direzione di Sanità'') in Rome until his death.〔
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